A sign marks the headquarters of Moderna Therapeutics, which is developing a vaccine against the coronavirus disease (COVID-19), in Cambridge, Massachusetts, May 18, 2020.
Brian Snyder | Reuters
Moderna will begin its late-stage trial testing a potential vaccine to prevent Covid-19 on July 27, according to a posting published Tuesday on ClinicalTrials.gov.
The trial will enroll 30,000 participants across 87 locations, according to the website. Participants in the experimental arm will receive a 100 microgram dose of the potential vaccine on the first day and another 29 days later. Some patients will also receive a placebo.
Moderna's experimental vaccine contains genetic material called messenger RNA, or mRNA. The mRNA is a genetic code that tells cells what to build — in this case, an antigen that may induce an immune response to the virus. It became the first candidate to enter a phase one human trial in March.
In May, the company released data from its early-stage trial, which showed the vaccine produced neutralizing antibodies against Covid-19 in at least eight participants. The vaccine also produced binding antibodies in all participants.
The effort by Moderna is one of several working on a potential vaccine for Covid-19, which has infected more than 13 million people and killed at least 573,200 across the globe as of Tuesday, according to data compiled by Johns Hopkins University. More than 100 vaccines are under development globally, according to the World Health Organization.
Earlier this month, pharmaceutical giant Pfizer released positive results from its closely watched early-stage human trial of a coronavirus vaccine.
The U.S. is aiming to deliver 300 million doses of a vaccine for Covid-19 by early 2021.
Scientists are still learning about key aspects of the virus, including how immune systems respond once a person is exposed. The answers, they say, may have important implications for vaccine development, including how quickly it can be deployed to the public.
Moderna's stock fell earlier this month after a report said its trial would be delayed.
Dr. Anthony Fauci, the nation's top infectious disease expert, has often touted Moderna's potential vaccine.
On Monday, he said he's "cautiously optimistic" scientists will be able to create at least one safe and effective vaccine by the end of the year or early 2021.
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July 14, 2020 at 10:18PM
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Moderna will begin late-stage coronavirus vaccine trial on July 27 - CNBC
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